Though mentioned before, semi-depressing facts of life: I circled the world on the LGA-ATL route...to be more correct, I did 28,461 miles on this route. And that excludes flights from JFK and EWR. Most miles on a route? as I suspected, JFK-CDG, with 76,062 miles (BIS) on the route. That's without flights to BRU or AMS, or even ORY.